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What should my health care professional know before I take Kaletra?

Serious drug interactions can occur when certain medicines are used together with lopinavir and ritonavir. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Some medicines can cause unwanted or dangerous effects when used with Kaletra. Your doctor may need to change your treatment plan if you use any of the following drugs:

alfuzosin;
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liver disease (especially hepatitis B or C);
heart disease or a heart rhythm disorder;
a personal or family history of Long QT Syndrome;
pancreas problems;
diabetes;
low levels of potassium in your blood;
a bleeding disorder such as hemophilia;
high cholesterol or triglycerides; or
if you have ever used a protease inhibitor in the past.

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Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the kaletra may be passed to the baby in your breast milk.
Kaletra is not approved for use by anyone younger than 14 days old. Premature infants should not receive the medication until it has been 14 days after their original due date.

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